Meridian Street Capital

Meridian Street Capital (MSC) is an early-stage venture capital firm founded in 2016 and headquartered in New York City. The firm invests exclusively at the intersection of healthcare and technology, backing founders at the pre-seed, seed, and Series A stages — often from day one. It runs a highly concentrated portfolio strategy, operating as a steadfast partner to a select group of founders rather than deploying capital broadly. The firm takes a hands-on, partnership-driven approach, offering deep operational, entrepreneurial, and healthcare investing expertise to its portfolio companies. With a strict no-ego, team-first culture, Meridian Street aims to serve as a meaningful, founder-aligned role player on cap tables. The firm is institutionally backed and currently investing out of its third fund, with total assets under management of approximately $60 million. Typical check sizes range from $100K to $5 million. Its portfolio spans digital health, AI diagnostics, behavioral health, virtual care, health IT, and consumer health. Notable portfolio companies include 1upHealth, Rula (formerly Path Mental Health), NoCD, Saferide Health, Included Health, Jona, Local Infusion, Isaac Health, Andros, Imvaria, and ClosedLoop.ai, among others. The firm's most recent investment was in CloudCruise in March 2026.