Frank Williams, Angel Investor

Frank Williams is Senior Advisor and Venture Partner at Define Ventures, where he supports early‑stage healthcare companies. He also leads Big Bend, LLC, advising entrepreneurs and investing in ventures such as Blackbird, Foodsmart, Helix, Private Health, Qualified Health, Verantos, and Wellth. Previously, Frank was Chairman and CEO of Evolent Health, where he guided the company’s growth to serve over 25 million patients nationwide. He also served as Executive Chairman of The Advisory Board Company, and currently sits on the Executive Committee and Board of UCSF Health. His career reflects a consistent focus on health equity, clinical performance improvement, and value‑based care. As an angel investor, his portfolio includes Qualified Health, Wellth, and Quartet Health, highlighting his interest in startups advancing mental health, nutrition, genomics, and care delivery for vulnerable populations.